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what is the formula to calculate sample size. 196 for 95 confidence level P population proportion expressed as decimal assumed to be 05 50 M Margin of Error at 5 005. Where n required sample size in each group m1is the mean change in pain score from baseline to week 24 in Drug A 5 m2is the mean change in pain score from baseline to week 24 in Drug B 45 the clinically important difference m1-m2 05 s is the standard deviation 1195.
The formula does not cover finite population. The sample size for the main study was 100 i did not use any sample size formula as the sampling procedure is convenience sampling and for the pilot study the sample size was nearly 50. With SS Sample Size for infinite population Z Z value eg.
This free sample size calculator determines the sample size required to meet a given set of constraints.
Necessary Sample Size Z-score2 StdDev 1-StdDev margin of error2. N Population size Z Critical value of the normal distribution at the required confidence level p Sample proportion e Margin of error. The sample size n can be calculated using the following formula. The formula does not cover finite population.